Obesity Drug Orlistat (Xenical) May Aid in Cancer Treatments

Five years ago, scientists at Wake Forest University School of Medicine were surprised to find the drug orlistat (Xenical or Alli) could kill cancer cells. Now, they report on how it works. The drug binds and interacts with a protein found in tumor cells, blocking its function and causing the cells to die.

Researches point out that Orlistat alone can not treat cancer, as it can act only in the digestive tract in humans. However, a greater understanding of how Orlistat functions with cancer cells may help in the development of a drug like orlistat that can go through the bloodstream to the site of the tumor.

Sanofi Pulls FDA Application for Anti-Obesity Drug, Acomplia

French pharmaceutical group Sanofi-Aventis said Friday it had withdrawn an application for regulatory approval for its anti-obesity drug Acomplia in the United States.
A panel of experts from the US Food and Drug Administration concluded earlier this month that the dieting treatment, referred to as rimonabant by the company, was unsafe and should not be sold in the United States.