Infection Expert Warns That MRSA May Be Unstoppable

Dr. Ron Najafi, CEO of NovaBay, describes MRSA (methicillin-resistant Staphylococcus aureus) as a slow-moving hurricane. "Once the ‘superbug’ hits a community or hospital," asks Dr. Najafi, "are populations ready to deal with it?"

His comment was prompted by the untimely death of college student Chris Steden to the disease, which infects 90,000 Americans in our hospitals every year, with 19,000 deaths reported annually.

The company is working on a compound, NVC-422, which may successfully fight many pathogens including MRSA. S. aureua breeds in the nose and on the skin. NovbaBay’s AgaNase formulation of NVC-422 for nasal applications, is an anti-infective, but not a conventional antibiotic. Topically applied to the lower nasal passage to eliminate colonization of S. aureus, including MRSA, AgaNase rapidly destroys a range of pathogens that include bacteria, yeast, and viruses.

Source: NobaBay Pharmaceuticals


  1. quiact says

    Sometimes, Death Is Good….. For A Vicious Unicellular Microorganism.

    There are a variety of different types of foreign bacterial infections one can get from many different sources, yet some are more common than others.

    If they are not beneficial for your physiology, they all should die in order to restore your health.

    Bacteria are a simple life form, yet are incredibly productive and efficient. As with other life forms, it exists to reproduce, and does so about every hour, and evolves and adapts to its environment as needed.

    To do this, it fully utilizes all available resources and energy to develop the protein that is essential for its survival, and bacteria have the ability to adapt as needed to assure this happens.

    It needs exactly 7 genes to produce the essential ribosomes for this to occur. Any more or less genes than 7, the bacteria is not maximizing its efficiency to survive and reproduce. Amazing.

    Strept infections are caused by what are called gram positive bacteria, and are the most common bacteria that infect others.

    Staph bacterial invasions are gram positive as well, yet it is the MRSA, Methicillin Resistant Staff Aureous bacteria of this type often are very difficult to treat normally when a patient suffers from their damage from being invaded by these bacteria.

    Another difficult situation is when a patient is infected by VRE, Vancomycin Resistant Enterococci, as well.

    These MRSA and VRE pathogenic or disease causing bacteria are the ones that are the most clinically concerning for the health care provider.

    In most cases, such bacteria invade a resident of a medical institution, and have proved to result in very dangerous infections.

    If so, they are called nosocomial infections, and such infections are not limited to resistant strains of bacteria.

    Greater than 5 percent of nosocomial infections are determined to be MRSA infections, others have determined. This results in about 100,000 serious hospital infections, as well as about 20,000 deaths from MRSA infections annually.

    Group A strep infections can cause diseases such as strep throat and pneumonia.

    Since there are several types of bacteria, a diagnostic test called a culture and sensitivity is usually performed to assure the correct antibiotic is selected for treatment, as the bacteria are identified with this method.

    Typically, fluid from the area suspected of being infected is obtained from the patient suspected to have an infection and smeared on what is called a petrie dish. And then these dishes are incubated for 2 to 3 days.

    Gram positive bacteria stain during this process a dark violet or blue. Gram negative bacteria would be pink in color, and are capable of harm as well to a human being.

    When the culture is complete, technology offers recommendations on the appropriate class or brand of antibiotic for this bacteria present in another person- presuming the bacteria will not be resistant to the antibiotic recommended, as this happens on occasion.

    Usually, classes of antibiotics that are used to treat gram positive strep infections that are not VRE or MRSA are cephalosporins, macrolides, or general penicillins.

    If the microbe that is causing the infection is resistant to the antibiotic from such classes that are administered to the infected patient, other options should be considered.

    With two antibiotics in particular, which are methicillin and vancomycin, which is the case with VRE and MRSA bacteria, then there are other more aggressive antibiotics that will be chosen for this patient.

    Such brands and types of antibiotics for MRSA and VRE bacteria include Zyvox, which has both IV and oral dosage options. There are also other antibiotics, such as Cubicin.

    However these antibiotics for antibiotic resistant bacteria are given usually due to infections that have progressed to a more serious nature within a patient infected in such a way.

    Progressive medical conditions include sepsis, or blood infection, osteomyelitis, or bone infection, or Pneumonia, which is a serious lung infection.

    A hospital stay is normally required with such patients, as the last antibiotics mentioned for MRSA and VRE bacterial infections are given by IV administration initially for several days, if not several weeks.

    There are numerous classes and types of antibiotics available, yet bacterial resistance to most of these antibiotics constantly remains serious concern for the health care provider, and the infected patient.

    With MRSA at the top of the list of concerns for the health care providers, this concern continues to progress, unfortunately.

    Medical institutions should possibly consider quarantine for those patients at their locations that have been determined to be infected with the MRSA bacteria.

    Dan Abshear

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