Beta-Amyloid Clearance from Brain May Underly Alzheimer’s Disease

Alzheimer’s disease is the most common cause of dementia in older adults, and affects as many as 5.1 million Americans. In Alzheimer’s disease, a protein fragment called beta-amyloid accumulates at abnormally high levels in the brain. In the the most common type of Alzheimer’s disease, late-onset Alzheimer’s, symptoms usually appear after age 65.

Now researchers have found that in late-onset Alzheimer’s disease, beta-amyloid is produced in the brain at a normal rate but is not cleared, or removed from the brain, efficiently. [Read more…]